- Union Pacific Cancer Cluster
- The Union Pacific Rail Yard, northeast of Houston, is contaminated by an ingredient that is associated with a cancer cluster. The chemicals are creosote and dioxin.
- A study showed that a large amount of the toxins were absorbed into groundwater and the soil surrounding the railyard. Researchers have discovered that residents who were affected are diagnosed with prostate, skin and bile duct cancers. This is a kind of liver cancer.
- Creosote
- Creosote is a compound that contains hundreds of chemicals used to preserve wood and other materials. It is suspected to be a carcinogen. In addition to cancer, creosote is also believed to cause eye damage and dermatitis.
- Houston's union pacific cancer cluster consists of a group that is infected by creosote. Union Pacific has been protesting the pollution for months and the community is demanding that they get rid of the contamination.
- Residents have fought for decades to force the company to eliminate their pollution. However, they haven't given up and are taking on the railroad company in federal court, hoping that the company will eventually take responsibility for the pollution.
- They claim that creosote has been an extremely toxic substance that has been infiltrating their homes and causing the people to become sick. They claim that the pollution causes children to develop cancer at five times the rate of national average.
- In addition to the health effects and causing environmental pollution, it is creating a situation where residents are losing their jobs and their homes. The pollution is leaching into the soil as well as the air and water in the area.
- According to the Houston Chronicle creosote was removed from the site by Southern Pacific for many decades before it was purchased by Union Pacific in 1997. Union Pacific didn't accept responsibility for the pollution until recently residents began a campaign.
- Despite their efforts, residents in the union pacific cluster suffer from esophageal and lung cancers. They also have high rates for childhood lymphoblastic leukemia.
- While scientists aren't able to pinpoint the exact reason behind the contamination, they believe that it is caused by chemicals in creosote. These chemicals have been linked with increased risk of esophagus, lung and throat cancers.
- The chemical is believed to be employed in a variety of ways, such as preservation of wood and to treat Ringworm. It is also used in insecticides and fungicides.
- Research has revealed that creosote chemicals have an oxidation-reduction process that renders them toxic. This could result in biodegradation and release toxic byproducts into the soil and water. However, this process can take time and is only effective if the initial chemical compounds are not too high in concentration.
- Dioxin
- Dioxin is one of many chemicals that has been linked to various types of cancers. It is harmful to the central nervous system, kidneys, liver and the liver.
- The chemical is present in the air, soil and water. It can be absorbed through the skin or swallowed by eating. It is a member of the so-called "dirty dozen" chemicals.
- The people who are exposed to high levels of dioxins through industrial or occupational accidents could be afflicted with health issues such as liver cancer, cancer, problems , and thyroid diseases. However, the effects on health of dioxin at low levels are unclear.
- Researchers are still studying the long-term effects of the contaminants. It has been linked with cancer in laboratory animals as well as those who live in contaminated areas.
- According to the World Health Organization (WHO) Dioxins have been found to increase the risk for certain types of cancer and can also affect the immune system and reproductive systems. They can also cause birth defects.
- Dioxins are absorbed by different ways, including eating foods high in fat or burning household trash and exposure to dangerous substances. Pesticides, industrial accidents and herbicides are a few other sources of dioxins found in our environment.
- If you smoke, you are more likely to have higher levels of dioxins than most people. You can lower the risk by quitting smoking.
- It is also important to eat a healthy, nutritious and balanced diets, including fruits, vegetables and grains. These foods can reduce or stop your exposure to dioxins, and their compounds.
- Healthy eating habits can help you avoid ailments like bronchus or lung cancers. It is also recommended to avoid eating meats and milk products which are high in fat.
- Choose foods that are low in fat will help to reduce your exposure to dioxins. It is important to consume plenty of fresh vegetables and fruits and to drink plenty of water.
- Dioxin, a toxic chemical, has been linked to several types of cancers including liver and breast cancer. It can cause harm to the brain, heart and lungs.
- Toxic Metals
- Metals like cadmium nickel, copper, chromium and iron are vital to our lives however they can become toxic if used in excess. They can also be present in small amounts in sewage and other polluting sources, and in electronic waste (ewaste).
- Many environmental heavy metals have been linked to a variety of illnesses such as cancer. Despite their importance in the development and onset of these diseases, it is not clear how they affect different organ systems.
- The chemical properties of individual ions as well as the specific cells to which they interact with to determine the toxicity of heavy metals. These interactions include the creation of ROS, inhibition enzymes that produce antioxidant compounds, and the inactivation of other proteins that may protect cells from toxic effects.
- In addition to these common mechanisms, every metal has its own unique toxicities. Copper and cadmium for instance, could weaken antioxidant defenses through the generation of superoxide anionradios (ROS) which harm mitochondrial and DNA functions. Additionally, these metals can attach to protein phosphatases (PP) and block glutathione peroxidase.
- Similar to lead and arsenic, arsenic and arsenic are often linked to the oxidative stress that results in inflammation and lipid peroxidation. These oxidative stressors can cause heart disease, lung cancer and other health issues.
- This is especially true for lead and arsenic that can trigger pro-inflammatory chemokines, which promote cancer cell growth. Railroad Cancer is possible that these chemicals may be able to interact with genes that are involved in cell cycle and DNA repair to enhance their mutagenic carcinogenic effects.
- Another significant role played by heavy metals is in enhancing the risk of prostate cancer. This is of great concern because prostate cancer is the most widespread form of cancer that men suffer from and is the most frequent cause of death due to the disease in the United States.
- Cadmium and copper can also increase the risk of coronary heart disease, and cardiovascular disease. These findings are particularly significant because they highlight the significance of toxic metals found in the environment in increasing cardiovascular risk. They also play a role as behavioral factors. However further research is required to better understand the connections and to determine causality.
- Pesticides
- Pesticides are chemicals that are used to control weeds, insects and fungi as well as other agricultural pests (Langley and Mort 2012; Mostafalou and Abdollahi 2017). They are vital in maintaining the production of agricultural products and provide food that is safe for humans. They can cause harm to the environment and human health if they are inhaled or come into direct contact with the skin.
- The United States uses over 1.1 billion pounds of pesticides each year. This is a large amount of harmful chemicals that can be inhaled, or ingestion. The use of pesticides are regulated by the Environmental Protection Agency.
- Pesticides are often employed on a variety of crops. However there is growing concern over their impact on the environment as well as human health. The World Health Organization has classified certain pesticides as carcinogenic or cause cancer.
- There is a growing effort to determine the relationship between exposure to pesticides and the development of cancer. These studies are conducted employing a mix of methods such as multilevel mixed effects models that are linear and Cox proportional hazards regressions.
- These methods are often used to assess the connection between a single chemical and health effects like cancer at a state, regional or national scale. This type of analysis is crucial because it provides a broad perspective of the possible relationships between environmental factors and health outcomes, and also allows for targeted research on specific chemicals.
- Another significant impact of pesticides on human health is the possibility of exposure through work-related actions that involve the application transport and storage of these substances. This is influenced by a variety of factors, such as the location of the worker as well as the products they employ.
- Pesticides can also be absorbed directly through the skin, or via inhalation. They may also be present as food. This could cause harm to the health of children and infants.
- In addition, pesticides can cause contamination of groundwater and the air which can cause respiratory disorders and kidney damage. These pollutants can be released by a variety of sources, including factories and waste incinerators. Dioxins are among the most hazardous, as they can cause cancer and other diseases like liver disease.
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